Triluma Cream is the gold-standard prescription treatment for melasma and moderate-to-severe
hyperpigmentation. This dermatologist-prescribed combination of Hydroquinone, Tretinoin, and Fluocinolone
works synergistically to lighten, exfoliate, and calm the skin.
Hydroquinone 4%
The most effective topical skin-lightening agent. Inhibits melanin production to fade dark patches,
brown spots, and uneven skin tone.
Tretinoin 0.05%
Accelerates skin cell turnover to exfoliate pigmented cells and enhance the penetration and efficacy of
Hydroquinone.
Fluocinolone 0.01%
A mild corticosteroid that reduces inflammation and irritation, making the treatment more tolerable and
preventing post-inflammatory darkening.
Usage Protocol
1 Once Daily at Night (start with every other night)
Apply a thin layer to affected areas only,
once daily at night. Clean and dry skin before application.
2Short-Term Use Only
Use for maximum 8 weeks as directed by your
doctor. Extended use requires medical supervision.
3Strict Sun Protection
SPF 30+ sunscreen is absolutely essential
every morning. Sun exposure will worsen melasma.
SAFETY INFORMATIONTriluma is a prescription-only medication by Galderma. Initial mild irritation, redness, or peeling may
occur. This is expected and usually resolves.
Do not use during pregnancy or breastfeeding.Not for use on large areas or under
occlusion. Avoid prolonged use without medical supervision.







